Create Online Store
What is Marfan Syndrome? Print E-mail
Written by Phillip LaVeque   
Tuesday, 27 October 2009

Marfan syndrome is an inherited disorder of the connective tissue in the body. It affects mainly the muscles, bones, eyes, and heart. It occurs in about 1 out of every 10,000 people.

What is going on in the body?

Marfan syndrome is caused when there is a mistake in the gene that makes fibrillin. Fibrillin is needed to support most of the tissues that make up the body. When the fibrillin is defective, problems can occur in muscles, bones, eyes, heart, and even the skin and lungs.

What are the causes and risks of the disease?
The life-threatening complications of Marfan syndrome are mostly due to the problems with the heart valves and the aorta. As the heart valves weaken, they stop pumping the blood as well as needed. This can lead to heart failure or changes in the heart rhythm. The valves can also become infected. This can lead to blood clots. The place where the aorta leaves the heart can become too wide and begin to tear. This is called an aortic dissection.

Problems with the lens and the retina of the eye can lead to blindness. If the spine begins to curve, it can lead to scoliosis.

What are the treatments for the disease?
Treatment of Marfan syndrome is aimed at preventing complications. Heart medicines, such as beta-blockers, may be used to reduce the stress on the heart valves and blood vessels. If the valves have been damaged, antibiotics may be needed at times to prevent a life-threatening infection of the heart valve. Valve replacement surgery may be needed. Eye surgery is sometimes done to correct some of the damage to the lens or the retina of the eye. This may help to prevent blindness. Bracing or surgery may be needed to correct a curvature of the spine. Hormone therapy may be used to keep young girls from becoming too tall. Physical therapy may help improve muscle tone, especially in infants and children who have this syndrome.

What are the side effects of the treatments?
Beta-blockers can cause side effects including tiredness, dizziness, and sexual side effects but these are not common in most people. They may also cause breathing problems in people who have asthma.

Antibiotics can cause stomach upset or allergic reactions in some people.

Surgical risks should be discussed with the surgeon or ophthalmologist, but any risks are usually outweighed by the benefits of the treatment.

Hormone therapy has side effects such as headaches and blood clots.

What happens after treatment for the disease?
Patients with Marfan syndrome need to be followed closely by their doctors to prevent complications from occurring.

How is the disease monitored?
Echocardiograms will need to be done frequently to check the heart and its valves. An ophthalmologist will need to check the eyes on a regular basis to prevent vision problems. As a child with Marfan syndrome grows, the spine will have to be checked for a curvature at least twice a year. Women with Marfan syndrome who become pregnant will have to be monitored closely as a "high-risk" pregnancy. Any new or worsening symptoms should always be reported to the doctor.


       $ave Money with Coupons:
        Grocery  Coupons

Men, Women Not needed to Make Babies?

U.S. researchers have found a way to coax human embryonic stem cells to turn into the types of cells that make eggs and sperm, shedding light on a stage of early human development that has not been fully understood. Read More
RocketTheme Joomla Templates
Disclaimer | Health Experts | Terms of Use | Privacy Policy | Contact
The content provided in this site is strictly for you to be able to find helpful information on improving your life and health. None of the information here is to be construed as medical advice. Only a Doctor can give you medical advice.