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What is Angina Pectoris? Print E-mail
Written by Kimberly Vaughn, MD   
Monday, 05 October 2009
Stable angina is pain, pressure, or a sense of heaviness in the chest beneath the breastbone. It is brought on by physical exertion and is relieved by rest. The discomfort or pain may also be felt in the left arm or shoulder, the neck, or the lower jaw. These are all areas of the body supplied by the same nerve that goes to the heart.
What is going on in the body?

Atherosclerosis, or hardening of the arteries, is a condition in which fatty deposits, also called plaque, form inside blood vessel walls. Atherosclerosis that involves the arteries supplying the heart is known as coronary artery disease. Plaque can block the flow of blood through the arteries. The tissues that normally receive blood from these arteries then begin to suffer damage from a lack of oxygen. When the heart does not have enough oxygen, it responds by causing the pain or discomfort known as angina.
What are the causes and risks of the condition?

Factors that increase the risk of stable angina include:
- smoking
- high blood pressure
- high blood cholesterol
- male gender
- increased age
- diabetes
- lack of exercise

What are the treatments for the condition?

Several types of medications are often used in combination to reduce the symptoms of stable angina.
- Beta-blockers, such as atenolol or metoprolol are used to decrease the work level of the heart, so that the same effort requires less oxygen.
- Nitrates, such as nitroglycerin or isosorbide mononitrate, help to expand the small arteries and veins. This improves the blood flow to the heart.
- Aspirin may prevent heart attacks. Warfarin may prevent blood clots. However, its use in treating stable angina remains controversial.

Calcium channel blockers, such as diltiazem, nifedipine, or verapamil, have been used for over 20 years to open the coronary arteries and lower high blood pressure. However, the findings of 2 recent studies have shown that people who take a calcium channel blocker have a much higher incidence of complications than people taking other medications for coronary artery disease and high blood pressure. One study, for example, showed that the risk of heart attack was 27% greater and the risk of congestive heart failure was 26% higher for those taking a calcium channel blocker. The American Heart Association recommends discussing risks and benefits of the medication with the healthcare provider.

Several procedures can be used to reduce the symptoms of stable angina, including:
- angioplasty, a procedure in which a tube with a balloon is inserted into the blocked artery and inflated. This reopens the artery and allows blood to flow.
- placing a stent, a rigid tube similar to a tiny drinking straw, into the artery at the reopened area to keep it from narrowing again
- laser surgery, which uses light waves to dissolve plaque
- atherectomy, which involves removing plaque that causes narrowing of a blood vessel

What are the side effects of the treatments?

Beta-blockers can cause:
- a slow heartbeat
- low blood pressure
- depression
- erectile dysfunction
- unpleasant dreams

Calcium channel blockers can cause:
- flushing
- nausea
- headache
- swelling of the ankles
- low blood pressure
- weakness
- a higher risk of heart attack and congestive heart failure

Nitrates can cause headaches and low blood pressure. Aspirin and warfarin increase the risk of bleeding. Surgery can result in infection, bleeding, and allergic reaction to anesthesia.
What happens after treatment for the condition?

Most individuals with stable angina are encouraged to begin a regular exercise program. A person with stable angina should make every effort to reduce coronary risk factors. This may include smoking cessation, control of other diseases such as diabetes and high blood pressure, and following a healthy diet for heart disease prevention. Medications may need to be adjusted to achieve the best response.
How is the condition monitored?

The person will have periodic examinations and tests by the healthcare provider to discuss episodes of stable angina. Any new or worsening symptoms should be reported to the healthcare provider.
 

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